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One of these subtypes is known as triple-negative breast cancer TNBC. TNBC grows rapidly. It also has a higher grade and tends to metastasize spread.
Approximately percent of breast cancers are triple negative, and it is more likely to affect younger people, African Americans or Hispanics, and those with a BRCA1 gene mutation. Triple negative breast cancer does not respond to hormonal therapy, such as Tamoxifen or aromatase inhibitors, or other therapies that target HER-2, such as Herceptin or Tykerb. Therefore, some patients are concerned that they are unable to do more to fight breast cancer recurrence.
If you're struggling to find what you need, call our Support line on 7 days a week, 8am-8pm. Triple negative breast cancer is a type of breast cancer that does not have receptors for the hormones oestrogen and progesterone or the protein HER2. You will have a small piece of breast tissue removed biopsy to test for the receptors. Triple negative breast cancer is more common in women under 40 and black women.
Women of color and young women may face elevated risks of developing triple-negative breast cancers, a type of cancer that spreads more quickly than most other types and doesn't respond well to hormone or targeted therapies, a study published in CANCERa peer-reviewed journal of the American Cancer Society, shows. Previous U. To conduct a larger study, researchers in the Georgia State University School of Public Health analyzed all breast cancer cases diagnosed during from the United States Cancer Statistics database, a surveillance system of cancer registries with data representing 99 percent of the U.
And if it turns out you have triple negative breast cancertreatment can become even more complex for your doctors—and confusing for you as the patient. To hopefully make things a little easier to understand, we spoke to experts on the frontlines to find out what you really need to know about triple negative breast cancer treatment. While the best source of information about your individual case is always going to be your care team, consider this a resource for getting yourself oriented.
Triple negative breast cancer is an uncommon type of breast cancer. Read about the symptoms, how it is diagnosed and treated, and what happens after treatment. Your doctor uses a sample of your cancer to test the cells for these receptors.
Triple-negative breast cancer is cancer that tests negative for estrogen receptors, progesterone receptors, and excess HER2 protein. These results mean the growth of the cancer is not fueled by the hormones estrogen and progesterone, or by the HER2 protein. So, triple-negative breast cancer does not respond to hormonal therapy medicines or medicines that target HER2 protein receptors. Still, other medicines are used to successfully treat triple-negative breast cancer.
Some questions you may have are:. The answer to those and other questions you have will depend on a lot of factors, such as the stage of the cancer and how well it responds to treatment. Keep reading to learn more about TNBC and your outlook.
Learn the latest information about triple negative breast cancer and meet up with other TNBC patients and caregivers. Travel grants available Knowing breast cancer basics can help you understand how triple negative breast cancer is different from other types of breast cancer. The type of breast cancer is determined by the presence or absence of receptors, proteins that live inside or on the surface of a cell and bind to something in the body to cause the cell to react.